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Contact About Exploring the stories of scientific discovery search for Search Search Christian B. Anfinsen The Christian B. Anfinsen Papers Christian Boehmer Anfinsen, Jr. (1916-1995), was an American biochemist who shared the 1972 Nobel Prize for work that helped explain the structure and composition of proteins in living cells. Virginia Apgar The Virginia Apgar Papers Virginia Apgar (1909-1974) was an American physician who is best known for the Apgar Score, a simple, rapid method for assessing newborn viability. Developed in the early 1950s and quickly adopted by obstetric teams, the method reduced infant mortality and laid the foundations of neonatology. Apgar scoring has been a standard obstetric practice for over fifty years. While best known for this achievement, Apgar was also a leader in the emerging field of anesthesiology during the 1940s and in the new field of teratology (the study of birth defects) after 1960. Oswald T. Avery The Oswald T. Avery Papers Oswald Theodore Avery (1877-1955) was a distinguished Canadian-born bacteriologist and research physician and one of the founders of immunochemistry. He is best known for his discovery that deoxyribonucleic acid (DNA) serves as genetic material. The work of Avery and the members of his team at the Rockefeller Institute, observes Nobel laureate Dr. Joshua Lederberg, was "the historical platform of modern DNA research" and "betokened the molecular revolution in genetics and biomedical science generally." Julius Axelrod The Julius Axelrod Papers Julius Axelrod (1912-2004) was an American pharmacologist and neuroscientist who shared the 1970 Nobel Prize in Physiology or Medicine for his discovery of the actions of neurotransmitters in regulating the metabolism of the nervous system. Paul Berg The Paul Berg Papers American biochemist Paul Berg (1926-2023) has been making outstanding contributions to biochemistry and molecular biology for over fifty years. Francis Crick The Francis Crick Papers The name of British Nobel laureate Francis Crick (1916-2004) is inextricably tied to the discovery of the double helix of deoxyribonucleic acid (DNA) in 1953, considered the most significant advance in the understanding of biology since Darwin’s theory of evolution. Michael E. DeBakey The Michael E. DeBakey Papers Michael E. DeBakey (1908-2008) was a legendary American surgeon, educator, and medical statesman. During a career spanning 75 years, his work transformed cardiovascular surgery, raised medical education standards, and informed national health care policy. He pioneered dozens of operative procedures such as aneurysm repair, coronary bypass, and endarterectomy, which routinely save thousands of lives each year, and performed some of the first heart transplants. His inventions included the roller pump (a key component of heart-lung machines) as well as artificial hearts and ventricular assist pumps. He was a driving force in building Houston’s Baylor University College of Medicine into a premier medical center, where he trained several generations of top surgeons from all over the world. Clarence Dennis The Clarence Dennis Papers American surgeon Clarence Dennis (1909-2005) invented one of the first heart-lung bypass machines, and in 1951 was the first to use it to perform open-heart surgery. Heart-lung bypass technologyperfected by Dennis, John Gibbon, and otherseliminated the major barriers to surgical treatment of cardiovascular conditions. During his 60-year career, Dennis’s surgical research produced a wide range of surgical techniques and tools, and important contributions to vascular physiology. He was also an outstanding medical educator, first at the University of Minnesota, then at SUNY Downstate Medical Center (where he chaired the department of surgery for 20 years), and finally at SUNY Stony Brook. Charles R. Drew The Charles R. Drew Papers African American surgeon Charles Richard Drew (1904-1950) has been called "the father of the blood bank," for his outstanding role in conceiving, organizing, and directing America’s first large-scale blood banking program during the early years of World War II. While best known for the blood bank work, Drew devoted much of his career to raising the standards of African American medical education at Howard University, where he trained a generation of outstanding surgeons, and worked to break through the barriers that segregation imposed on Black physicians. His premature death in a car accident generated enduring stories that he was a victim of medical segregation, though this was repeatedly proved false. John E. Fogarty The John E. Fogarty Papers John Edward Fogarty (1913-1967) was an American legislator who became known as "Mr. Public Health" for his outstanding advocacy of federal funding for medical research, health education, and health care services. As Democratic representative for Rhode Island, he served in the U.S. House of Representatives from 1941 to 1967, and chaired the House Appropriations Subcommittee for the Departments of Labor and Health, Education, and Welfare from 1949. During his congressional tenure Fogarty championed a vast expansion of the National Institutes of Health, as well as aid to medical schools, libraries, and programs for blind, deaf, and developmentally challenged children. He sponsored or contributed to virtually every piece of health-related legislation introduced during these years. Rosalind Franklin The Rosalind Franklin Papers Rosalind Elsie Franklin (1920-1958) was a British chemist and crystallographer who is best known for her role in the discovery of the structure of DNA. It was her x-ray diffraction photos of DNA and her analysis of that dataprovided to Francis Crick and James Watson without her knowledgethat gave them clues crucial to building their correct theoretical model of the molecule in 1953. While best known for this work, Franklin also did important research into the micro-structure and properties of coals and other carbons, and spent the last five years of her career elucidating the structure of plant viruses, notably tobacco mosaic virus. Donald S. Fredrickson The Donald S. Fredrickson Papers Donald Fredrickson (1924-2002) was an American physiologist and biomedical research leader who made significant contributions to medicine over the course of four decades. Fredrickson’s system of classification of abnormalities in fat transport was adopted by the World Health Organization as an international standard for identifying increased risks of coronary artery disease linked to the consumption of fats and cholesterol. He also discovered two genetic diseases caused by disorders in lipid metabolism. As director of the National Institutes of Health (NIH), Fredrickson mediated between scientists and the federal government during debates over the direction of medical research policy, funding, and the dangers of genetic engineering during the second half of the 1970s. Edward D. Freis The Edward D. Freis Papers Edward David Freis (1912-2005) was an American cardiologist who made key contributions to clinical and scientific understanding of cardiovascular disease. He is best known as the father of the first double-blind, multi-institutional controlled clinical trial of cardiovascular drugs, the Veterans Administration Cooperative Study on Antihypertensive Agents. This landmark study demonstrated that treating high blood pressurehypertensionwith medication could dramatically reduce disability and death from stroke, congestive heart failure, and other cardiovascular diseases. Freis received a Lasker Award in 1971 in recognition of this work. The study provided the impetus for the establishment of the National High Blood Pressure Education Program by the National Heart, Lung, and Blood Institute in 1972, and launched an era of preventive cardiology. Mike Gorman The Mike Gorman Papers Thomas Francis Xavier (Mike) Gorman (1913-1989) was a well-known journalist, author, publicist, and crusader for health...

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